#Coda 2 cobalt professional#
In order to ensure satisfactory results, particularly for large stains, we recommend to contact a professional dry cleaner. In all cases, we recommend contacting a professional dry cleaning. These tips are purely recommendations and cannot guarantee complete stain removal. The balloon is available in diameters of 32 mm and 40 mm, with maximum inflation volumes of 34 mL and 40 mL. This applies especially to microfibre textiles. The CODA Balloon Catheter (Cook Incorporated, Bloomington, IN) is a semicompliant, polyurethane balloon used for expansion of abdominal (AAA) and thoracic (TAA) aortic aneurysm endografts and/or temporary occlusion of large vessels. It may also be necessary to use a hairdryer to avoid leaving edge marks. Make sure to dry the fabric fully before use. In all cases, we recommend to test stain-removal agents on an inconspicuous area first, to see if there is any effect on the cover. Remove greasy stains by using appropriate detergents or solvents. Edge marks can be avoided by dabbing gently in circular motions towards the centre of the stain with a clean lint-free cloth.
Remove non-greasy stains by carefully dabbing with a lintfree cloth or sponge wrung out in warm water. Liquids must be soaked up with an absorbent napkin or cloth. Any loose particles must be vacuum cleaned before further cleaning. However, we cannot guarantee complete stain removal.įirst, scrape off any liquids or hardened residues with a spoon or a scoop before you proceed. Several ordered water molecules have been observed on the protein surface and in the active-site channel their structural locations coincide remarkably with those of related water molecules found in the crystal structure of the phylogenetically distant superoxide dismutase from yeast.If you act quickly, it is not difficult to remove spills and prevent stains from forming. An additional copper ligand, compatible with a water molecule, is observed at 2.38 A from Cu2+ in the active-site channel, at the supposed binding site of the O2- anion substrate. The least-squares superposition of the metals ligands and the catalytically important Arg141 of the native and Co-substituted enzyme yields a root-mean-square value of 0.401 A, the largest deviation occurring at the Co2+ ligand Asp81. Co2+ is in tetrahedral co-ordination, while the Cu2+ ligands show an uneven distortion from the square planar geometry. The co-ordination geometry of the metal center in the active site is fairly well preserved when compared with the native Cu,Zn bovine enzyme.
The subunit has as its structural scaffolding the conventional SOD-flattened antiparallel eight-stranded beta-barrel, with three external loops.
The dimeric molecule of the enzyme is composed of two identical subunits related by a non-crystallographic 2-fold axis. The R-factor for the 18,964 unique reflections in the resolution range from 10.0 to 2.0 A is 0.176 for a model comprising 2188 protein atoms and 200 solvent molecules the root-mean-square deviation from the ideal bond lengths is 0.010 A, and the average atomic temperature factor is 26.5 A2. The structure has been solved by molecular replacement techniques using the Cu,Zn bovine enzyme as a search model, and refined by molecular dynamics with the crystallographic pseudo-energy term, followed by conventional crystallographic refinement. The crystals belong to space group P2(1)2(1)2(1) with cell constants: a = 51.0, b = 147.6, c = 47.5 A, and contain one dimeric molecule of 32,000 M(r) per asymmetric unit. The semisynthetic Co-substituted bovine erythrocyte superoxide dismutase (SOD) has been crystallized in a new crystalline form and the structure determined at 2.0 A (1 A = 0.1 nm) resolution.
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